Condensins Promote Coorientation of Sister Chromatids During Meiosis I in Budding Yeast
نویسندگان
چکیده
منابع مشابه
Condensins promote coorientation of sister chromatids during meiosis I in budding yeast.
The condensin complex is a key determinant of higher-ordered chromosome structure. We show here that the complex is also important for the correct alignment of chromosomes on the meiosis I spindle. Unlike during mitosis and meiosis II, when sister chromatids attach to microtubules emanating from opposite spindle poles (biorientation), accurate meiosis I chromosome segregation requires that sist...
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The chiasma is a structure that forms between a pair of homologous chromosomes by crossover recombination and physically links the homologous chromosomes during meiosis. Chiasmata are essential for the attachment of the homologous chromosomes to opposite spindle poles (bipolar attachment) and their subsequent segregation to the opposite poles during meiosis I. However, the overall function of c...
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ژورنال
عنوان ژورنال: Genetics
سال: 2010
ISSN: 1943-2631
DOI: 10.1534/genetics.110.115139